Plus, if something seemingly can’t be terminated with that, 99% of the time it’s a kernel level lockup (e.g. disk IO). At which point you only have 2 options: kill it via a kernel debugger or (the more likely scenario) perform a reboot.

Oh you mean Android Studio automagically “updating” your versions so that your build breaks and you spent 3 hours figuring out what just happened without you even touching anything?