Aw shucks I don’t know anything about AMD, sorry. I doubt any of the nvidia-libs related stuff would do anything on AMD. I did learn a bunch of troubleshooting tips while trying to get it working though, hopefully they can help:

• as always, check system logs. You can use journalctl in the terminal (look online for more tips, like how to filter for a specific time range), or your distro might come with a GUI (Gnome and KDE both have one, though the Gnome one is much easier to use imho)
• Insta360 Studio has log files, you can find them in the bottle sandboxed filesystem, pretty sure it was under AppData, so the path on the host would look something like $HOME/.var/app/com.usebottles.bottles/data/bottles/Insta360/drive_c/users/steamuser/AppData/...
• in the Bottles flatpak, after installing Insta360 Studio in the bottle, next to the Insta360 Studio shortcut there should be a triple-dot menu with some options, try clicking “Launch with Terminal” so you can see the terminal logs as the application is launching
  • though for some reason I noticed that on Bluefin this option doesn’t work…in that case maybe try running the entire Bottles flatpak from the terminal: flatpak run com.usebottles.bottles, though I haven’t tried this specifically
• try running tools like GPU_Caps_Viewer and GPU-Z inside the same Bottle to see if they detect the GPU, and what capabilities they report (for the Nvidia GPU you need the CUDA capability, not sure what might be needed for AMD)
• search for Insta360 Studio under https://appdb.winehq.org/, see if anybody else reported getting it working on AMD, and how they did it
• in Bottles, try different runners, like the proton runner or the caffe runner
• ask an AI like ChatGPT or Gemini, the ones with web search access are pretty good at solving Linux issues from what I’ve heard

Unfortunately this is just as tedious as it sounds. I hate trying to get Windows software running in Linux (aside from games, those generally work and you can just check protondb for support). Luckily Insta360 Studio was the last remaining software that I still needed a Windows VM, so once I finally figured it out I could retire Windows for good.